Hot Glue is a thermoplastic adhesive, it was used by some to bioproof their implants. This is a terrible idea. Please do not do that.
Hot Glue can be contaminated with literally anything, you have no idea where it comes from. Depending which sort you get, your body may destroy the glue, leaving you with an exposed implant. Hot glue is worse for bioproofing than Sugru, and Sugru is so bad there is no way to describe how bad it is.